Information Library and Case Reports
Many thousands of dogs and hundreds of cats have received Masivet as part of their treatment protocol for inoperable, high grade mast cell tumours since the autumn of 2009.
If you have an interesting or unique case report and you would like to share this with other veterinary professionals on this page, please send an email via the link below and we shall share case reports on our face-book and website pages. Your case reports can help other vets to understand more about cancer in pets: for example when they may need to seek help from a veterinary cancer specialist, what other treatment options are possible and how Masivet might be able to help certain pets in their care.
Daisy was one of the first dogs in the UK to receive Masivet. She had multiple, widespread, high grade 3 mast cell tumours - including spread to her lymph nodes - following an initial surgical removal of a small skin mass. Masivet was not available at that time, so Daisy received both traditional and novel cytotoxic chemotherapies but the tumours failed to respond. Daisy was a very lucky girl and received Masivet treatment following a special request by her veterinary oncologist to AB Science in France. There was a complete response within a few weeks of starting treatment and Daisy remained in complete remission for 6 months on treatment. She was a complicated case and her masses did eventually come back but the tumours remained stable - and Daisy remained very well - for more than 18 months. Her owner was so impressed and delighted with all the extra wonderful months she shared with Daisy, that she became one of our UK Vet Advisors! So you can ask Christine all about Daisy.”
Bella is a lovely Boston terrier who had a very large, 1 kg abdominal mass removed early in 2017. Pathology results confirmed that this tumour contained diffusely spindloid cells with a positive signal for c- Kit and was sub-classified as a GI Stromal Tumour (GIST). C-Kit targeted TKIs have been shown in human oncology to slow down the rate of regrowth or recurrence of this type of tumour. Bella started Masivet treatment soon after recovery from her incredible surgery and remains very well. She is pictured here with her loving mum and dad at her veterinary clinic in Powys.
Roux is a fabulous Dogue de Bordeaux, treated with Masivet for inoperable cutaneous lymphoma. Following several different types of cytotoxic chemotherapy treatments, none of which were effective, the decision was made in the summer of 2015 to remove Roux’s ear as the lymphoma seemed to be contained in this area. However, just two weeks after her surgery, five new masses appeared around the surgical site and down onto her neck. This was clearly not good news for Roux – but her veterinary oncologist recommended Masivet treatment to try to slow down the progression of this cancer. By November 2015 Roux was confirmed to be in remission – and she is still in remission today! Her owners sent us this fabulous recent photo of Roux enjoying a run on the beach at West Kilbride on the West Coast of Scotland in July 2017, with a note to let us know that Roux has been in remission since November 2015 and “has a great quality of life”. Many thanks to Roux’s Dad, who has given us permission to share this story about their gorgeous girl in order to offer hope to others who may receive the sad news that their beloved dogue has cancer.